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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6
All Species:
8.79
Human Site:
Y1155
Identified Species:
16.11
UniProt:
Q03468
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03468
NP_000115.1
1493
168416
Y1155
D
E
K
L
G
L
S
Y
K
R
E
R
P
S
Q
Chimpanzee
Pan troglodytes
XP_507781
1491
168031
Y1153
D
E
K
L
G
L
S
Y
K
R
E
G
P
S
Q
Rhesus Macaque
Macaca mulatta
XP_001107536
1496
168876
Y1158
D
E
K
L
G
L
S
Y
K
R
E
R
P
S
Q
Dog
Lupus familis
XP_534944
1486
168108
L1148
S
I
H
E
K
Q
G
L
S
D
R
R
E
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001100766
1325
148468
G1008
R
A
S
S
V
G
F
G
E
E
A
D
A
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508174
968
109820
Q651
L
S
N
P
D
G
S
Q
G
T
E
T
S
A
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24368
1027
118855
E710
R
E
A
L
R
V
S
E
P
K
A
P
K
A
P
Honey Bee
Apis mellifera
XP_001120586
932
107557
R615
V
L
E
D
P
R
Q
R
R
L
F
K
T
N
D
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
R692
I
E
P
P
K
R
E
R
K
A
N
Y
Q
V
D
Sea Urchin
Strong. purpuratus
XP_001193315
953
107227
A636
H
G
H
M
S
S
S
A
S
S
S
K
H
L
S
Poplar Tree
Populus trichocarpa
XP_002307656
1206
134941
K888
F
L
T
N
K
I
L
K
N
P
Q
Q
R
R
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWY3
1057
122611
W740
K
K
I
V
S
D
N
W
N
D
P
P
K
R
E
Baker's Yeast
Sacchar. cerevisiae
P40352
1085
124509
G768
R
E
R
A
W
R
I
G
Q
K
R
E
V
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
83.3
N.A.
N.A.
70.1
N.A.
44.6
N.A.
N.A.
N.A.
N.A.
20
31.4
20.6
36.4
Protein Similarity:
100
99.4
97.9
89.1
N.A.
N.A.
76.4
N.A.
52.2
N.A.
N.A.
N.A.
N.A.
35.7
43.8
35.7
45.8
P-Site Identity:
100
93.3
100
13.3
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
0
13.3
6.6
P-Site Similarity:
100
93.3
100
13.3
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
40
26.6
13.3
20
Percent
Protein Identity:
29.4
N.A.
N.A.
23.5
28.4
N.A.
Protein Similarity:
44.9
N.A.
N.A.
38.2
43.9
N.A.
P-Site Identity:
0
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
0
8
0
8
16
0
8
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
24
0
0
8
8
8
0
0
0
16
0
8
0
0
16
% D
% Glu:
0
47
8
8
0
0
8
8
8
8
31
8
8
0
8
% E
% Phe:
8
0
0
0
0
0
8
0
0
0
8
0
0
0
8
% F
% Gly:
0
8
0
0
24
16
8
16
8
0
0
8
0
8
0
% G
% His:
8
0
16
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
8
8
0
0
8
8
0
0
0
0
0
0
0
16
% I
% Lys:
8
8
24
0
24
0
0
8
31
16
0
16
16
0
0
% K
% Leu:
8
16
0
31
0
24
8
8
0
8
0
0
0
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
8
0
16
0
8
0
0
8
0
% N
% Pro:
0
0
8
16
8
0
0
0
8
8
8
16
24
0
8
% P
% Gln:
0
0
0
0
0
8
8
8
8
0
8
8
8
0
24
% Q
% Arg:
24
0
8
0
8
24
0
16
8
24
16
24
8
16
0
% R
% Ser:
8
8
8
8
16
8
47
0
16
8
8
0
8
39
16
% S
% Thr:
0
0
8
0
0
0
0
0
0
8
0
8
8
0
0
% T
% Val:
8
0
0
8
8
8
0
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
24
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _